HuagongsheHuagongshe Chemistry Print Report · For research reference only
Leucine, N-carboxy-, N-benzyl ester, L- → N-[N-[(Phenylmethoxy)carbonyl]-L-leucyl]-L-norleucinol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Leucine, N-carboxy-, N-benzyl ester, L- | HCID 74840 | — |
| Reactant | (2S)-2-Amino-1-hexanol | HCID 5494388 | — |
| Product | N-[N-[(Phenylmethoxy)carbonyl]-L-leucyl]-L-norleucinol | HCID 15168139 | 58% |
Reaction Steps
N-[(Phenylmethoxy)carbonyl]-L-leucine was used instead of 1-[[(phenylmethoxy)carbonyl]amino]cyclohexanecarboxylic acid and L-norleucinol was used instead of L-valinol in the process according to Example 1 to obtain 421 mg (58%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957205B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-46fbd7eba0c941df8539366d0d654826 |
| Source note | uspto-grants-2015_02 |