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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1851896Generated: November 2, 2026

1-Phenylpropan-1-amine → 1-(2-Bromobenzyl)-N-(1-phenylpropyl)-1H-indole-5-carboxamide

https://huagongshe.com/reaction/1851896

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Phenylpropan-1-amineHCID 18054—
Reactant1-(2-Bromobenzyl)-2,3-dimethyl-1H-indole-5-carboxylic acidHCID 71074806—
Product1-(2-Bromobenzyl)-N-(1-phenylpropyl)-1H-indole-5-carboxamideHCID 71074804—

Reaction Steps

The title compound was prepared following the same protocol as described in Step 4, Example 38, using 1-phenylpropan-1-amine instead of the (S)-1-(4-nitrophenyl)ethanamine hydrochloride, and 1-(2-Bromobenzyl)-2,3-dimethyl-1H-indole-5-carboxylic acid instead of the 1-(4-bromobenzyl)-1H-indole-5-carboxylic acid. ESI-MS (m/z): 447/449 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957093B2
Source datasetuspto-grants-2015_02
ORD IDord-43aa4a5a582940658c7f6ca951d02628
Source noteuspto-grants-2015_02