Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1851898Generated: October 25, 2026

(1S)-1-(4-Nitrophenyl)ethan-1-amine → 4'-[(2,3-Dimethyl-5-{[(1s)-1-(4-Nitrophenyl)ethyl]carbamoyl}-1h-Indol-1-Yl)methyl]biphenyl-2-Carboxylic Acid

https://huagongshe.com/reaction/1851898

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S)-1-(4-Nitrophenyl)ethan-1-amineHCID 1268055—
ReactantHCID 71074664HCID 71074664—
Product4'-[(2,3-Dimethyl-5-{[(1s)-1-(4-Nitrophenyl)ethyl]carbamoyl}-1h-Indol-1-Yl)methyl]biphenyl-2-Carboxylic AcidHCID 53239854—

Reaction Steps

The title compound was prepared following the same general protocol as described in Steps 8-9, Example 1, using (S)-α-methyl-4-nitrobenzylamine and 1-((2′-(tert-butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid. LC-MS 548 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957093B2
Source datasetuspto-grants-2015_02
ORD IDord-904b3af2e95f4257bba46230f71f18ad
Source noteuspto-grants-2015_02