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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1851899Generated: November 1, 2026

(R)-(+)-beta-Methylphenethylamine → (R)-4'-((2,3-dimethyl-5-(2-phenylpropylcarbamoyl)-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid

https://huagongshe.com/reaction/1851899

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-(+)-beta-MethylphenethylamineHCID 1547949—
Reactant1-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acidHCID 71074664—
Product(R)-4'-((2,3-dimethyl-5-(2-phenylpropylcarbamoyl)-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acidHCID 71074790—

Reaction Steps

The title compound was prepared following the same general protocol as described in Steps 8-9, Example 1, using (R)-2-phenylpropan-1-amine and 1-((2′-(tert-butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid. LC-MS 517 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957093B2
Source datasetuspto-grants-2015_02
ORD IDord-da35a500b32c4dbba87752f7e5fb808f
Source noteuspto-grants-2015_02