Benzo-1,3-dioxole-5-methylamine → HCID 71074731, compound

HRID 1851902Notes

Reaction equation

HRID 1851902 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][NH2:11])=[CH:9][C:4]=2[O:3][CH2:2]1.C([O:16][C:17]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[C:25]1[CH:30]=[CH:29][C:28]([CH2:31][N:32]2[C:40]3[C:35](=[CH:36][C:37]([C:41](O)=[O:42])=[CH:38][CH:39]=3)[C:34]([CH3:44])=[C:33]2[CH3:45])=[CH:27][CH:26]=1)=[O:18])(C)(C)C>>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][NH:11][C:41]([C:37]3[CH:36]=[C:35]4[C:40](=[CH:39][CH:38]=3)[N:32]([CH2:31][C:28]3[CH:27]=[CH:26][C:25]([C:20]5[C:19]([C:17]([OH:18])=[O:16])=[CH:24][CH:23]=[CH:22][CH:21]=5)=[CH:30][CH:29]=3)[C:33]([CH3:45])=[C:34]4[CH3:44])=[O:42])=[CH:9][C:4]=2[O:3][CH2:2]1

Participants

3

Reactant 2

HCID 75799Benzo-1,3-dioxole-5-methylamineHCID 710746641-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid

Product 1

HCID 71074731HCID 71074731, compound

Procedure

The title compound was prepared following the same general protocol as described in Steps 8-9, Example 1, using benzo[d][1,3]dioxol-5-ylmethanamine and 1-((2′-(tert-butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid. LC-MS 533 (M+H).

Sources & evidence

ORD record
ord-d4a325ebff8e4107a86bd9363467fcb4
Source dataset
uspto-grants-2015_02
Patent number
US08957093B2

Reaction notes

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