(2-Thienylmethyl)amine → HCID 71074894, compound

HRID 1851907Notes

Reaction equation

HRID 1851907 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][NH2:7].C([O:12][C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[C:21]1[CH:26]=[CH:25][C:24]([CH2:27][N:28]2[C:36]3[C:31](=[CH:32][C:33]([C:37](O)=[O:38])=[CH:34][CH:35]=3)[C:30]([CH3:40])=[C:29]2[CH3:41])=[CH:23][CH:22]=1)=[O:14])(C)(C)C>>[CH3:41][C:29]1[N:28]([CH2:27][C:24]2[CH:25]=[CH:26][C:21]([C:16]3[C:15]([C:13]([OH:14])=[O:12])=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:22][CH:23]=2)[C:36]2[C:31]([C:30]=1[CH3:40])=[CH:32][C:33]([C:37](=[O:38])[NH:7][CH2:6][C:2]1[S:1][CH:5]=[CH:4][CH:3]=1)=[CH:34][CH:35]=2

Participants

3

Reactant 2

HCID 34005(2-Thienylmethyl)amineHCID 710746641-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid

Product 1

HCID 71074894HCID 71074894, compound

Procedure

The title compound was prepared following the same general protocol as described in Steps 8-9, Example 1, using 2-thiophenemethylamine and 1-((2′-(tert-butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid.

Sources & evidence

ORD record
ord-5bfcc461d32f4c3597e054e09d2032a9
Source dataset
uspto-grants-2015_02
Patent number
US08957093B2

Reaction notes

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