5-Methyl-2-furylmethylamine → HCID 71074856, compound

HRID 1851908Notes

Reaction equation

HRID 1851908 reaction equation
[CH3:1][C:2]1[O:6][C:5]([CH2:7][NH2:8])=[CH:4][CH:3]=1.C([O:13][C:14]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[C:22]1[CH:27]=[CH:26][C:25]([CH2:28][N:29]2[C:37]3[C:32](=[CH:33][C:34]([C:38](O)=[O:39])=[CH:35][CH:36]=3)[C:31]([CH3:41])=[C:30]2[CH3:42])=[CH:24][CH:23]=1)=[O:15])(C)(C)C>>[CH3:42][C:30]1[N:29]([CH2:28][C:25]2[CH:26]=[CH:27][C:22]([C:17]3[C:16]([C:14]([OH:15])=[O:13])=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:23][CH:24]=2)[C:37]2[C:32]([C:31]=1[CH3:41])=[CH:33][C:34]([C:38](=[O:39])[NH:8][CH2:7][C:5]1[O:6][C:2]([CH3:1])=[CH:3][CH:4]=1)=[CH:35][CH:36]=2

Participants

3

Reactant 2

HCID 27246835-Methyl-2-furylmethylamineHCID 710746641-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid

Product 1

HCID 71074856HCID 71074856, compound

Procedure

The title compound was prepared following the same general protocol as described in Steps 8-9, Example 1, using 5-methyl-2-furanylmethylamine and 1-((2′-(tert-butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid. LC-MS 493 (M+H).

Sources & evidence

ORD record
ord-a781923382994a98b22f281d63925141
Source dataset
uspto-grants-2015_02
Patent number
US08957093B2

Reaction notes

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