4-Methylbenzylamine → HCID 71074982, compound

HRID 1851928Notes

Reaction equation

HRID 1851928 reaction equation
[CH3:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=1.C([O:14][C:15]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[C:23]1[CH:28]=[CH:27][C:26]([CH2:29][N:30]2[C:38]3[C:33](=[CH:34]C(C(O)=O)=C[CH:37]=3)[C:32]([CH3:42])=[C:31]2[CH3:43])=[CH:25][CH:24]=1)=[O:16])(C)(C)C>>[CH3:37][C:38]1[N:30]([CH2:29][C:26]2[CH:25]=[CH:24][C:23]([C:18]3[C:17]([C:15]([OH:14])=[O:16])=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:28][CH:27]=2)[C:31]2[C:43]([C:33]=1[CH3:34])=[CH:18][C:17]([C:15](=[O:14])[NH:7][CH2:6][C:5]1[CH:8]=[CH:9][C:2]([CH3:1])=[CH:3][CH:4]=1)=[CH:42][CH:32]=2

Participants

3

Reactant 2

HCID 660354-MethylbenzylamineHCID 710746641-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid

Product 1

HCID 71074982HCID 71074982, compound

Procedure

The title compound was prepared following the same general protocol as described in Steps 8-9, Example 1, using 4-methylbenzylamine and 1-((2′-(tert-butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid.

Sources & evidence

ORD record
ord-8003f0d850604ac5b6543904fcadc6fe
Source dataset
uspto-grants-2015_02
Patent number
US08957093B2

Reaction notes

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