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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1851933Generated: October 31, 2026

3-Fluoro-4-methoxybenzylamine → 4'-((5-(3-fluoro-4-methoxybenzylcarbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid

https://huagongshe.com/reaction/1851933

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-methoxybenzylamineHCID 14392588—
Reactant1-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acidHCID 71074664—
Product4'-((5-(3-fluoro-4-methoxybenzylcarbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acidHCID 71074948—

Reaction Steps

The title compound was prepared following the same general protocol as described in Steps 8-9, Example 1, using 3-fluoro-4-methoxybenzylamine and 1-((2′-(tert-butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid. LC-MS 537 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957093B2
Source datasetuspto-grants-2015_02
ORD IDord-13dd2cf2a37f44e5a31f95603d5467e9
Source noteuspto-grants-2015_02