HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Ethoxycarbonylphenyl)boronic acid → 1-((3'-(Ethoxycarbonyl)-[1,1'-biphenyl]-2-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Ethoxycarbonylphenyl)boronic acid | HCID 3249312 | — |
| Reactant | 1-(2-Bromobenzyl)-2,3-dimethyl-1H-indole-5-carboxylic acid | HCID 71074806 | — |
| Product | 1-((3'-(Ethoxycarbonyl)-[1,1'-biphenyl]-2-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid | HCID 71074535 | — |
Reaction Steps
The title compound was prepared following the same protocol as described in Step 5, Example 38, using 1-(2-bromobenzyl)-2,3-dimethyl-1H-indole-5-carboxylic acid instead of the (S)-1-(4-bromobenzyl)-N-(1-(4-nitrophenyl)ethyl)-1H-indole-5-carboxamide and the (3-(ethoxycarbonyl)phenyl)boronic acid instead of the phenylboronic acid. ESI-MS (m/z): 428 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957093B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-c114e2b10b38478d8bd3a2b77b4dd04c |
| Source note | uspto-grants-2015_02 |