HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpropan-1-amine → tert-Butyl 4'-((3-methyl-5-((1-phenylpropyl)carbamoyl)-1H-indol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpropan-1-amine | HCID 18054 | — |
| Reactant | 1-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-3-methyl-1H-indole-5-carboxylic acid | HCID 71074350 | — |
| Product | tert-Butyl 4'-((3-methyl-5-((1-phenylpropyl)carbamoyl)-1H-indol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylate | HCID 86674543 | — |
Reaction Steps
The title compound was prepared following the same protocol as described in Step 8, Example 1, using the 1-((2′-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-3-methyl-1H-indole-5-carboxylic acid instead of the 1-((2′-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid and the 1-phenylpropan-1-amine instead of the (S)-1-(4-bromophenyl)ethanamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957093B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-6b2217257a0e4580a31d418dcb09fa1f |
| Source note | uspto-grants-2015_02 |