化工社化工社 化学情報印刷レポート · 研究参考用
(1S)-1-(4-Nitrophenyl)ethan-1-amine → (S)-tert-Butyl 4'-((5-((1-(4-nitrophenyl)ethyl)carbamoyl)-3-methyl-1H-indol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (1S)-1-(4-Nitrophenyl)ethan-1-amine | HCID 1268055 | — |
| 反応物 | 1-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-3-methyl-1H-indole-5-carboxylic acid | HCID 71074350 | — |
| 生成物 | (S)-tert-Butyl 4'-((5-((1-(4-nitrophenyl)ethyl)carbamoyl)-3-methyl-1H-indol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylate | HCID 86674544 | — |
反応手順
The title compound was prepared following the same protocol as described in Step 8, Example 1, using the 1-((2′-(tert-butoxycarbonyl)-[1,1′-biphenyl]-4-yl)methyl)-3-methyl-1H-indole-5-carboxylic acid instead of the 1-((2′-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid and the (S)-1-(4-nitrophenyl)ethanamine instead of the (S)-1-(4-bromophenyl)ethanamine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08957093B2 |
| 出典データセット | uspto-grants-2015_02 |
| ORD ID | ord-2812cb7c76c74812956c0cae665834ac |
| 出典メモ | uspto-grants-2015_02 |