HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86674546, compound → HCID 71074594, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86674546 | HCID 86674546 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 71074594 | HCID 71074594 | — |
Reaction Steps
A solution of (S)-tert-butyl 4′-((2,3-dimethyl-5-((1-(3-(prop-1-en-2-yl)phenyl)ethyl)carbamoyl)-1H-indol-1-yl)methyl)-[1,1′-biphenyl]-2-carboxylate (0.13 mmol, 1 equiv.) in ethanol (5 mL) was degassed with argon. A hint of Pd/C 10% was added to the solution. The suspension was stirred at rt for 5 h under H2 bubbling. The resulting mixture was then filtered and concentrated. The obtained oil was used without further purification. ESI-MS (m/z): 601 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957093B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-9e1718a3faf348fa89c288c84fb062fe |
| Source note | uspto-grants-2015_02 |