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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1851959Generated: November 2, 2026

HCID 86674546, compound → HCID 71074594, compound

https://huagongshe.com/reaction/1851959

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86674546HCID 86674546—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 71074594HCID 71074594—

Reaction Steps

A solution of (S)-tert-butyl 4′-((2,3-dimethyl-5-((1-(3-(prop-1-en-2-yl)phenyl)ethyl)carbamoyl)-1H-indol-1-yl)methyl)-[1,1′-biphenyl]-2-carboxylate (0.13 mmol, 1 equiv.) in ethanol (5 mL) was degassed with argon. A hint of Pd/C 10% was added to the solution. The suspension was stirred at rt for 5 h under H2 bubbling. The resulting mixture was then filtered and concentrated. The obtained oil was used without further purification. ESI-MS (m/z): 601 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957093B2
Source datasetuspto-grants-2015_02
ORD IDord-9e1718a3faf348fa89c288c84fb062fe
Source noteuspto-grants-2015_02