HCID 55278252, compound → HCID 53389240, compound

HRID 1851980Notes

Reaction equation

HRID 1851980 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([C@H:10]([NH2:14])[CH:11]([CH3:13])[CH3:12])[CH:7]=[CH:8][CH:9]=1)([CH3:3])[CH3:2].C([O:19][C:20]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[C:28]1[CH:33]=[CH:32][C:31]([CH2:34][N:35]2[C:43]3[C:38](=[CH:39][C:40]([C:44](O)=[O:45])=[CH:41][CH:42]=3)[C:37]([CH3:47])=[C:36]2[CH3:48])=[CH:30][CH:29]=1)=[O:21])(C)(C)C>>[CH:1]([C:4]1[CH:5]=[C:6]([C@H:10]([NH:14][C:44]([C:40]2[CH:39]=[C:38]3[C:43](=[CH:42][CH:41]=2)[N:35]([CH2:34][C:31]2[CH:30]=[CH:29][C:28]([C:23]4[C:22]([C:20]([OH:21])=[O:19])=[CH:27][CH:26]=[CH:25][CH:24]=4)=[CH:33][CH:32]=2)[C:36]([CH3:48])=[C:37]3[CH3:47])=[O:45])[CH:11]([CH3:13])[CH3:12])[CH:7]=[CH:8][CH:9]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 55278252HCID 55278252, compoundHCID 710746641-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid

Product 1

HCID 53389240HCID 53389240, compound

Procedure

The title compound was prepared following the same general protocol as described in Step 8-9, Example 1, using the (R)-1-(3-isopropylphenyl)-2-methylpropan-1-amine and the 1-((2′-(tert-butoxycarbonyl)-[1,1′-biphenyl]-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid. ESI-MS (m/z): 573 [M+H]+.

Sources & evidence

ORD record
ord-2a5f0f4615694074afe1a0cda36a6b05
Source dataset
uspto-grants-2015_02
Patent number
US08957093B2

Reaction notes

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