HRID1851991

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1084922

未命名化合物

结构：Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)OC(C)(C)C)cc2)c2ccc(C(=O)O)cc12

HCID71074664

未命名化合物

PRODUCTS

生成物

结构：Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@H](C)c3ccncc3)cc12

HCID71074921

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the same general protocol as described in Step 8-9, Example 1, using the (R)-1-(pyridin-4-yl)ethanamine and the 1-((2′-(tert-butoxycarbonyl)-[1,1′-biphenyl]-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid. ESI-MS (m/z): 504 [M+H]+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-286dff9d21f346c98e4ed5c1ba2993cc
来源数据集: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08957093B2
来源说明: uspto-grants-2015_02

反应 SMILES

[N:1]1[CH:6]=[CH:5][C:4]([C@H:7]([NH2:9])[CH3:8])=[CH:3][CH:2]=1.C([O:14][C:15]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[C:23]1[CH:28]=[CH:27][C:26]([CH2:29][N:30]2[C:38]3[C:33](=[CH:34][C:35]([C:39](O)=[O:40])=[CH:36][CH:37]=3)[C:32]([CH3:42])=[C:31]2[CH3:43])=[CH:25][CH:24]=1)=[O:16])(C)(C)C>>[CH3:43][C:31]1[N:30]([CH2:29][C:26]2[CH:27]=[CH:28][C:23]([C:18]3[C:17]([C:15]([OH:16])=[O:14])=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:24][CH:25]=2)[C:38]2[C:33]([C:32]=1[CH3:42])=[CH:34][C:35]([C:39](=[O:40])[NH:9][C@@H:7]([C:4]1[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=1)[CH3:8])=[CH:36][CH:37]=2