(S)-1-(p-tolyl)ethanamine → HCID 53481932, compound

HRID 1852001Notes

Reaction equation

HRID 1852001 reaction equation
[C:1]1([CH3:10])[CH:6]=[CH:5][C:4]([C@@H:7]([NH2:9])[CH3:8])=[CH:3][CH:2]=1.C([O:15][C:16]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[C:24]1[CH:29]=[CH:28][C:27]([CH2:30][N:31]2[C:39]3[C:34](=[CH:35][C:36]([C:40](O)=[O:41])=[CH:37][CH:38]=3)[C:33]([CH3:43])=[C:32]2[CH3:44])=[CH:26][CH:25]=1)=[O:17])(C)(C)C>>[CH3:44][C:32]1[N:31]([CH2:30][C:27]2[CH:28]=[CH:29][C:24]([C:19]3[C:18]([C:16]([OH:17])=[O:15])=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:25][CH:26]=2)[C:39]2[C:34]([C:33]=1[CH3:43])=[CH:35][C:36]([C:40](=[O:41])[NH:9][C@H:7]([C:4]1[CH:5]=[CH:6][C:1]([CH3:10])=[CH:2][CH:3]=1)[CH3:8])=[CH:37][CH:38]=2

Participants

3

Reactant 2

HCID 7015759(S)-1-(p-tolyl)ethanamineHCID 710746641-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid

Product 1

HCID 53481932HCID 53481932, compound

Procedure

The title compound was prepared following the same general protocol as described in Step 8-9, Example 1, using the (S)-1-(p-tolyl)ethanamine and the 1-((2′-(tert-butoxycarbonyl)-[1,1′-biphenyl]-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid. ESI-MS (m/z): 517 [M+H]+.

Sources & evidence

ORD record
ord-029e2ccec82841549fce91b8a6e49611
Source dataset
uspto-grants-2015_02
Patent number
US08957093B2

Reaction notes

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