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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1852002Generated: October 28, 2026

2-(4-Bromophenyl)propan-2-amine → 4'-((5-((2-(4-bromophenyl)propan-2-yl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid

https://huagongshe.com/reaction/1852002

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Bromophenyl)propan-2-amineHCID 23009116—
Reactant1-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acidHCID 71074664—
Product4'-((5-((2-(4-bromophenyl)propan-2-yl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acidHCID 53481928—

Reaction Steps

The title compound was prepared following the same general protocol as described in Step 8-9, Example 1, using the 2-(4-bromophenyl)propan-2-amine and the 1-((2′-(tert-butoxycarbonyl)-[1,1′-biphenyl]-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid. ESI-MS (m/z): 595/597 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957093B2
Source datasetuspto-grants-2015_02
ORD IDord-5cd47e7067024536a312b6ca21a7bf1c
Source noteuspto-grants-2015_02