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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 185202Generated: October 27, 2026

8-(benzyloxy)-5-[(1R)-2-bromo-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl]quinolin-2(1H)-one → 5-[1-[tert-butyl(dimethyl)silyl]oxy-2-[9-[4-[[3-(cyclohexyl-hydroxy-phenylmethyl)-1,2,4-triazol-1-yl]methyl]piperidin-1-yl]nonylamino]ethyl]-8-phenylmethoxy-1H-quinolin-2-one

https://huagongshe.com/reaction/185202

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-(benzyloxy)-5-[(1R)-2-bromo-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl]quinolin-2(1H)-oneHCID 21880641—
Reactant(1-{[1-(9-aminononyl)piperidin-4-yl]methyl}-1H-1,2,4-triazol-3-yl)(cyclohexyl)phenylmethanolHCID 59145971—
Product5-[1-[tert-butyl(dimethyl)silyl]oxy-2-[9-[4-[[3-(cyclohexyl-hydroxy-phenylmethyl)-1,2,4-triazol-1-yl]methyl]piperidin-1-yl]nonylamino]ethyl]-8-phenylmethoxy-1H-quinolin-2-oneHCID 91168301—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-5c01e028fe4844b9a9efeb230eb6d424
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)