Ethyl 2,3-dimethyl-1H-indole-5-carboxylate → HCID 71074910, compound

HRID 1852034Notes

Reaction equation

HRID 1852034 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([C:10]=1[CH3:11])=[CH:8][C:7]([C:12]([O:14][CH2:15][CH3:16])=[O:13])=[CH:6][CH:5]=2.Br[CH2:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]2[C:26]([S:31]([NH:34][C:35]([CH3:38])([CH3:37])[CH3:36])(=[O:33])=[O:32])=[CH:27][CH:28]=[CH:29][CH:30]=2)=[CH:21][CH:20]=1>>[C:35]([NH:34][S:31]([C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=1[C:22]1[CH:23]=[CH:24][C:19]([CH2:18][N:3]2[C:4]3[C:9](=[CH:8][C:7]([C:12]([O:14][CH2:15][CH3:16])=[O:13])=[CH:6][CH:5]=3)[C:10]([CH3:11])=[C:2]2[CH3:1])=[CH:20][CH:21]=1)(=[O:33])=[O:32])([CH3:38])([CH3:37])[CH3:36]

Participants

3

Reactant 2

HCID 612460Ethyl 2,3-dimethyl-1H-indole-5-carboxylateHCID 15282100[2'-(N-t-Butylsulfamoyl)biphenyl-4-yl]methyl bromide

Product 1

HCID 71074910HCID 71074910, compound

Procedure

The title compound was prepared following the same general protocol as described in Step 6, Example 1, using the ethyl 2,3-dimethyl-1H-indole-5-carboxylate and 4′-(bromomethyl)-N-(tert-butyl)-[1,1′-biphenyl]-2-sulfonamide.

Sources & evidence

ORD record
ord-af7e3827851d4644b4d18821517caf18
Source dataset
uspto-grants-2015_02
Patent number
US08957093B2

Reaction notes

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