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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1852042Generated: November 2, 2026

HCID 86674571, compound → HCID 71478388, compound

https://huagongshe.com/reaction/1852042

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86674571HCID 86674571—
SolventDichloromethaneHCID 6344—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 71478388HCID 71478388—

Reaction Steps

The solution of (S)-1-((2′-(((tert-Butyldimethylsilyl)oxy)carbamoyl)-[1,1′-biphenyl]-4-yl)methyl)-N-(1-(3-isopropylphenyl)ethyl)-2,3-dimethyl-1H-indole-5-carboxamide in DCM (3 mL) and TFA (0.5 mL) was stirred for 1 h at rt. The solvent was removed and the residue was purified by reverse phase prep-HPLC (MeOH/Acetonitrile/water) to obtain the title compound. ESI-MS (m/z): 560 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957093B2
Source datasetuspto-grants-2015_02
ORD IDord-a60d1a5487894f4ba939b3fc41795045
Source noteuspto-grants-2015_02