1-Hexyne, 6-fluoro- → HCID 46183231, compound

HRID 1852340Notes

Reaction equation

HRID 1852340 reaction equation
FC[C:3]1[N:4]=[N:5][N:6]([CH2:8][N:9]2[C:19]3[C:14](=[CH:15][C:16]([S:20]([N:23]4[CH2:27][CH2:26][CH2:25][C@H:24]4[CH2:28][O:29][C:30]4[CH:35]=[CH:34][C:33]([F:36])=[CH:32][C:31]=4[F:37])(=[O:22])=[O:21])=[CH:17][CH:18]=3)[C:12](=[O:13])[C:10]2=[O:11])[CH:7]=1.[F:38][CH2:39][CH2:40][CH2:41][CH2:42]C#C.FCC#C>>[F:38][CH2:39][CH2:40][CH2:41][CH2:42][C:3]1[N:4]=[N:5][N:6]([CH2:8][N:9]2[C:19]3[C:14](=[CH:15][C:16]([S:20]([N:23]4[CH2:27][CH2:26][CH2:25][C@H:24]4[CH2:28][O:29][C:30]4[CH:35]=[CH:34][C:33]([F:36])=[CH:32][C:31]=4[F:37])(=[O:22])=[O:21])=[CH:17][CH:18]=3)[C:12](=[O:13])[C:10]2=[O:11])[CH:7]=1

Participants

4

Reactant 3

HCID 97621-Hexyne, 6-fluoro-HCID 137718Propyne, 3-fluoro-HCID 46183000HCID 46183000, compound

Product 1

HCID 46183231HCID 46183231, compound

Procedure

is prepared according for the procedure for compound 6, with the exception that 6-fluorohex-1-yne is used in place of the (3-fluoroprop-1-yne). For the preparation of [18F]9, 6-[18F]fluorohex-1-yne is used in place of 3-fluoroprop-1-yne.

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-64a2ae10818948bc8e27f1bf587b1c33
Source dataset
uspto-grants-2015_02
Patent number
US08961930B2

Reaction notes

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