Iron chloride (FeCl3) → Iron oleate

Participants

Reaction Steps

The SPIONs were synthesized according to a previously reported procedure. Briefly, the iron-oleate complexes were prepared by reacting sodium oleate and iron (III) chloride. The SPIONS were synthesized with an average size of 13 nm. For the synthesis of SPIONs with an average size of 13 nm, 18 g of iron-oleate complex with 20 mmol concentration and 5.7 g of oleic acid with 20 mmol concentration were dissolved in 100 g of 1-octadecene at room temperature. The reaction mixture was degassed at 80° C. for 2 hrs. The mixture was heated to a reflux temperature at a heating rate of 3° C./minute and then kept for 30 minutes under an inert atmosphere. The container vessel was rapidly cooled down to the room temperature after the reaction occurred. This was followed by the addition of 500 mL of acetone to start the precipitation of SPIONs. The SPIONs were separated by a centrifuge and dispersed in hexane.

Provenance & Evidence