Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate) | HCID 6639 | — |
| Reactant | 2-Nitrophenol | HCID 6947 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-(2-chloroethoxy)-2-nitrobenzene | HCID 4362487 | — |
Reaction Steps
2-Nitro-phenol (168.7 g) and toluene-4-sulfonic acid 2-chloroethyl ester (100 g) were dissolved in 500 ml DMF and were stirred for 1 h at 110-120° C. after careful addition of 199 g potassium carbonate. The reaction mixture was poured in a mixture of crushed ice and water (8 L) which was vigorously stirred. The residue was filtered off, washed several times with water and dried. Yield: 100-120 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08962338B2 |
|---|
| Source dataset | uspto-grants-2015_02 |
|---|
| ORD ID | ord-aaa3f2253eee4557a9cc2742595f9d62 |
|---|
| Source note | uspto-grants-2015_02 |
|---|
