Potassium Carbonate → HCID 86689311, compound

Participants

Reaction Steps

A dry toluene (50 mL) suspension of 4-nitroindan-5-yl triflate (3.11 g, 10.0 mmol), 3-aminobenzonitrile (1.77 g, 15.0 mmol), potassium carbonate (1.38 g, 10.0 mmol), tetrakis(triphenylphosphine)palladium (0.57 g, 0.50 mmol), and triphenylphosphine (0.26 g, 1.00 mmol) was refluxed for 66 hours. After cooling on standing, insoluble was removed by filtration. The filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (ethyl acetate/hexane=1/5) to give the titled compound as orange crystal (0.84 g, yield 30%).

Provenance & Evidence