tert-Butyl (4-aminophenyl)carbamate → HCID 131732467, compound

HRID 1852500Notes

Reaction equation

HRID 1852500 reaction equation
O([C:9]1[CH:18]=[CH:17][C:16]2[CH2:15][CH2:14][CH2:13][CH2:12][C:11]=2[C:10]=1[N+:19]([O-:21])=[O:20])S(C(F)(F)F)(=O)=O.[C:22]([O:26][C:27](=[O:36])[NH:28][C:29]1[CH:34]=[CH:33][C:32]([NH2:35])=[CH:31][CH:30]=1)([CH3:25])([CH3:24])[CH3:23]>>[N+:19]([C:10]1[C:11]2[CH2:12][CH2:13][CH2:14][CH2:15][C:16]=2[CH:17]=[CH:18][C:9]=1[NH:35][C:32]1[CH:31]=[CH:30][C:29]([NH:28][C:27](=[O:36])[O:26][C:22]([CH3:24])([CH3:23])[CH3:25])=[CH:34][CH:33]=1)([O-:21])=[O:20]

Participants

3

Reactant 2

HCID 688611tert-Butyl (4-aminophenyl)carbamateHCID 86689304HCID 86689304, compound

Product 1

HCID 131732467HCID 131732467, compoundYield 49%

Procedure

1-Nitro-5,6,7,8-tetrahydronaphthalen-2-yl triflate (3.25 g, 10 mmol) and tert-butyl(4-aminophenyl)carbamate (2.08 g, 10 mmol) were used in a process similar to Example 1(1) to give the titled compound as a red solid (1.88 g, yield 49%).

Sources & evidence

ORD record
ord-70991247abeb4711a986faa64c9ca720
Source dataset
uspto-grants-2015_02
Patent number
US08962613B2

Reaction notes

Loading…