4-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine → N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(2-oxo-7-(trifluoromethoxy)quinolin-1(2H)-yl)acetamide

HRID 185270Notes

Reaction equation

HRID 185270 reaction equation
[Br:21][c:22]1[c:23](-[c:28]2[n:29][cH:30][n:31][nH:32]2)[c:24]([NH2:27])[s:25][cH:26]1.[O:1]=[c:2]1[n:3]([CH2:17][C:18](=[O:19])[OH:20])[c:4]2[cH:5][c:6]([O:12][C:13]([F:14])([F:15])[F:16])[cH:7][cH:8][c:9]2[cH:10][cH:11]1>>[O:1]=[c:2]1[n:3]([CH2:17][C:18](=[O:20])[NH:27][c:24]2[c:23](-[c:28]3[n:29][cH:30][n:31][nH:32]3)[c:22]([Br:21])[cH:26][s:25]2)[c:4]2[cH:5][c:6]([O:12][C:13]([F:14])([F:15])[F:16])[cH:7][cH:8][c:9]2[cH:10][cH:11]1

Participants

3

Reactant 2

HCID 596366864-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amineHCID 687849432-(2-oxo-7-(trifluoromethoxy)quinolin-1(2H)-yl)acetic acid

Product 1

HCID 56668697N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(2-oxo-7-(trifluoromethoxy)quinolin-1(2H)-yl)acetamide

Sources & evidence

ORD record
ord-fb7cae7e26c64b049a49e37f07688f51
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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