HCID 68288804, compound → HCID 66546509, compound

Participants

Reaction Steps

To a solution of the compound prepared in Example 33 (0.0121 g) in anhydrous THF (1.0 mL) at room temperature under N2 was added tBuOK (0.0030 g). The reaction immediately turned yellow, then a darker brown. After 2 hours, the reaction was partitioned between DCM and saturated NaHCO3 solution and separated. The aqueous layer was reextracted with DCM. The organic layers were combined and washed with water, and brine, then dried with Na2SO4 and concentrated. Purification by preparative TLC yielded the title compound (0.0074 g) having the following physical data.

Provenance & Evidence