4-Ethynyl-N,N-dimethylaniline → HCID 136352224, compound

Participants

Reaction Steps

7-(4-dimethylaminophenyl)ethynyl-2-isoquinolin-3-yl-chromen-4-one oxime was prepared in 8% overall yield using the method described in example 24, starting from 7-bromo-2-isoquinolin-3-yl-chromen-4-one O-tert-butyl oxime (example 2B) and 4-dimethylaminophenylacetylene. The title compound was isolated as an orange solid and as a 95/5 mixture of Z/E oxime isomers.

Provenance & Evidence