Benzenamine, 3-ethynyl- → HCID 136352226, compound

Participants

Reaction Steps

7-(3-aminophenyl)ethynyl-2-isoquinolin-3-yl-chromen-4-one oxime was prepared in 17% overall yield using the method described in example 24, starting from 7-bromo-2-isoquinolin-3-yl-chromen-4-one O-tert-butyl oxime (example 2B) and 3-aminophenylacetylene. The title compound was isolated as a yellow solid and as a 95/5 mixture of Z/E oxime isomers.

Provenance & Evidence