1-Chloro-2-ethynylbenzene → HCID 137126429, compound

Participants

Reaction Steps

7-(2-chlorophenyl)ethynyl-2-isoquinolin-3-yl-chromen-4-one oxime was prepared in 10% overall yield using the method described in example 24, starting from 7-bromo-2-isoquinolin-3-yl-chromen-4-one O-tert-butyl oxime (example 2B) and 2-chlorophenylacetylene. The title compound was isolated as an orange solid and as a 80/20 mixture of Z/E oxime isomers.

Provenance & Evidence