3-Butyn-1-OL → HCID 136352236, compound

Participants

Reaction Steps

7-(4-Hydroxy-but-1-ynyl)-2-isoquinolin-3-yl-chromen-4-one oxime was prepared in 10% overall yield using the method described in example 24, starting from 7-bromo-2-isoquinolin-3-yl-chromen-4-one O-tert-butyl oxime (example 2B) and 3-butyn-1-ol. The title compound was isolated as a yellow solid and as a 70/30 mixture of Z/E oxime isomers.

Provenance & Evidence