2'-Hydroxypropiophenone → HCID 67195807, 화합물

HRID 1853298노트

반응식

HRID 1853298 반응식
O[C:2]1[CH:7]=[CH:6][CH:5]=C[C:3]=1[C:8](=[O:11])[CH2:9][CH3:10].[CH:12]1[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH:15]=[C:14]([C:22]([O:24][CH3:25])=O)[N:13]=1>>[CH:12]1[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH:15]=[C:14]([C:22]2[O:24][C:25]3[C:3]([C:8](=[O:11])[C:9]=2[CH3:10])=[CH:2][CH:7]=[CH:6][CH:5]=3)[N:13]=1

참가 물질

3

반응물 2

HCID 691332'-HydroxypropiophenoneHCID 725374Methyl 3-isoquinolinecarboxylate

생성물 1

HCID 67195807HCID 67195807, 화합물수율 76%

실험 절차

2-Isoquinolin-3-yl-3-methyl-chromen-4-one was prepared in 76% yield using method A, starting from 2′-hydroxy-propiophenone and methyl isoquinoline-3-carboxylate.

출처 및 근거

ORD 기록
ord-ec4696bd7da14ff1b73b683809990233
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08962627B2

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