HCID 86673071, compound → HCID 86673070, compound

Participants

Reaction Steps

A solution of 6-(3-Methoxy-prop-1-ynyl)-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one O-tert-butyl-oxime (example 83B) (30 mg, 0.075 mmol) and 10% platinum black (10 mg) in ethyl acetate (10 ml) was hydrogenated at room temperature under 1 atmosphere of hydrogen during 48 hours. The catalyst was removed by filtration over Celite® and the filtrates concentrated to dryness to yield the title compound (18 mg, 60%) as a yellow solid that was used for the next step without further purification.

Provenance & Evidence