HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4-Difluoropiperidine → HCID 131732478, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4-Difluoropiperidine | HCID 2758352 | — |
| Reactant | 6-(2-chloro-ethoxy)-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one O-tert-butyl oxime | HCID 86673076 | — |
| Product | HCID 131732478 | HCID 131732478 | — |
Reaction Steps
6-(4,4-difluoro-piperidin-1-y)-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one oxime, hydrochloride was prepared in 48% overall yield using the method described in example 87, starting from 6-(2-chloro-ethoxy)-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one O-tert-butyl oxime (example 87B) and 4,4-difluoropiperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962627B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-faff74ac4c8e4b3bb74264052bf92840 |
| Source note | uspto-grants-2015_02 |