HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Hydroxy-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime → 6-[2-(4-Fluoro-phenyl)-ethoxy]-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Hydroxy-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime | HCID 86673101 | — |
| Reactant | 1-(2-Chloro-ethyl)-4-fluorophenyl hydrochloride | HCID 86673105 | — |
| Product | 6-[2-(4-Fluoro-phenyl)-ethoxy]-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one oxime | HCID 136352240 | — |
Reaction Steps
6-[2-(4-Fluoro-phenyl)-ethoxy]-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one oxime was prepared in 18% overall yield using the method described in example 127, starting from 6-Hydroxy-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime (example 127B) and 1-(2-Chloro-ethyl)-4-fluorophenyl hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962627B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-8842faec6bde4c1cbc9b27953b2018ff |
| Source note | uspto-grants-2015_02 |