HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Pyridinepropanol → 6-(3-Pyridin-4-yl-propoxy)-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one oxime, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Pyridinepropanol | HCID 72923 | — |
| Reactant | Pyridine, 4-(3-chloropropyl)-, hydrochloride | HCID 205441 | — |
| Reactant | 6-Hydroxy-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime | HCID 86673101 | — |
| Product | 6-(3-Pyridin-4-yl-propoxy)-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one oxime, hydrochloride | HCID 137187587 | — |
Reaction Steps
6-(3-Pyridin-4-yl-propoxy)-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one oxime, hydrochloride was prepared in 7% overall yield using the method described in example 127, starting from 6-hydroxy-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl oxime (example 127A) and 4-(3-Chloro-propyl)-pyridine hydrochloride, prepared from 4-pyridine propanol (U.S. Pat. No. 6,362,336).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962627B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-c521c6d6562242c3ac8d3026b1457bfe |
| Source note | uspto-grants-2015_02 |