1-(2-Bromoethyl)-4-chlorobenzene → 6-[2-(4-Chloro-phenyl)-ethoxy]-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one oxime

Participants

Role	Name	HCID	Charge
Reactant	1-(2-Bromoethyl)-4-chlorobenzene	HCID 23029	—
Reactant	6-Hydroxy-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one O-tert-butyl-oxime	HCID 86673073	—
Product	6-[2-(4-Chloro-phenyl)-ethoxy]-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one oxime	HCID 86673111	—

Reaction Steps

6-[2-(4-Chloro-phenyl)-ethoxy]-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one oxime was prepared in 28% overall yield using the method described in example 85, starting from 6-hydroxy-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one O-tert-butyl oxime (example 81A) and 1-(2-Bromo-ethyl)-4-chloro-benzene.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08962627B2
Source dataset	uspto-grants-2015_02
ORD ID	ord-7e170740e3e644eb970b31284550fecc
Source note	uspto-grants-2015_02