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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1853363Generated: October 31, 2026

HCID 65481651, compound → HCID 89106853, compound

https://huagongshe.com/reaction/1853363

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 65481651HCID 65481651—
Reactant6-Hydroxy-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one O-tert-butyl-oximeHCID 86673073—
ProductHCID 89106853HCID 89106853—

Reaction Steps

N-(5-Fluoro-pyridin-2-yl)-2-{4-hydroxyimino-2-pyrrolo[1,2-c]pyrimidin-3-yl-4H-chromen-6-yloxy}-acetamide was prepared in 2% overall yield using the method described in example 147, starting from 6-hydroxy-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one O-tert-butyl-oxime (example 81A) and 2-Bromo-N-(5-fluoro-pyridin-2-yl)-acetamide (Bioorg. Med. Chem. 11 (2003) 2769-2782).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08962627B2
Source datasetuspto-grants-2015_02
ORD IDord-d88367572a414956bbaa40250e455c40
Source noteuspto-grants-2015_02