HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1853390Generated: October 31, 2026
1-Bromo-2-methylpropane → HCID 117224638, compound
https://huagongshe.com/reaction/1853390
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Bromo-2-methylpropane | HCID 6555 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloro-5-pyrimidinol | HCID 14595700 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 117224638 | HCID 117224638 | — |
Reaction Steps
0.80 mg (6.13 mmol) 2-chloro-5-hydroxypyrimidine, 1.26 g (9.19 mmol) 1-bromo-2-methylpropane and 1.69 g (12.26 mmol) K2CO3 are added to 10 mL DMF and stirred at 80° C. over night. Afterwards the reaction is quenched by the addition of water and extracted with EtOAc. The org. layers are combined, dried over MgSO4, filtered and the solvent is removed in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08962641B2 |
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| Source dataset | uspto-grants-2015_02 |
|---|
| ORD ID | ord-5dc7a01ec3c447a08b62c1c2d84226bd |
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| Source note | uspto-grants-2015_02 |
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