Thionyl Chloride → 2-(Bicyclo(2.2.1)heptan-2-yl)acetyl chloride

Participants

Reaction Steps

2-Norbornaneacetic acid (Aldrich, Catalog #127264, CAS #1007-01-8, 2.01 g, 13.0 mmol) was dissolved in thionyl chloride (7 mL, 96 mmol). The reaction was heated to reflux for 5 hours. The reaction mixture was concentrated in vacuo to provide the title compound as a colorless oil (2.24 g, 100%) that was used without additional purification.

Provenance & Evidence