Thionyl Chloride → 3-(1-Adamantyl)propanoyl chloride

HRID 1853403Notes

Reaction equation

[C:1]12([CH2:11][CH2:12][C:13]([OH:15])=O)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.S(Cl)([Cl:18])=O>>[C:1]12([CH2:11][CH2:12][C:13]([Cl:18])=[O:15])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 7134943-(1-Adamantyl)propanoic acid

Product 1

HCID 155333063-(1-Adamantyl)propanoyl chloride

Procedure

3-(1-Adamantyl)propanic acid was reacted with thionyl chloride as describe in Example 10A to provide the title compound as colorless oil.

Sources & evidence

ORD record: ord-727f89c4cf0049f498f9646e85fd5046
Source dataset: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08962639B2

Reaction notes

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