3-amino-2-ethyl-3H,4H-thieno[2,3-d]pyrimidin-4-one → HCID 49872535, compound

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Reaction Steps

3-Amino-2-ethylthieno[2,3-d]pyrimidin-4(3H)-one and 1-adamantaneacetyl chloride were reacted as described in Example 5 to provide the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 1.20 (t, J=7.3 Hz, 3H), 1.59-1.74 (m, 12H), 1.93-1.98 (m, 3H), 2.08-2.18 (m, 2H), 2.56-2.80 (m, 2H), 7.39 (d, J=6.0 Hz, 1H), 7.59 (d, J=6.0 Hz, 1H), 10.83 (s, 1H) ppm; MS (DCI/NH3) m/z 372 (M+H)+; Elemental Analysis: Calculated for C20H25N3O2S: C, 63.74; H, 6.85; N, 11.15. Found: C, 63.77; H, 6.89; N, 11.13.

Provenance & Evidence