反应详情

3-Amino-2-phenyl-4(3H)-quinazolinone and the product of Example 13A were reacted as described in Example 5 to provide the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 0.93-1.13 (m, 2H), 1.23-1.33 (m, 6H), 1.51-1.65 (m, 6H), 1.85-1.89 (m, 3H), 1.96-2.08 (m, 2H), 7.44-7.55 (m, 3H), 7.58-7.64 (m, 3H), 7.75 (d, J=7.8 Hz, 1H), 7.89-7.94 (m, 1H), 8.18 (dd, J=8.0, 1.2 Hz, 1H), 11.06 (s, 1H) ppm; MS (DCI/NH3) m/z 428 (M+H)+; Elemental Analysis: Calculated for C27H29N3O2: C, 75.85; H, 6.84; N, 9.83. Found: C, 75.75; H, 6.97; N, 9.84.