1-Adamantaneacetyl chloride → HCID 49872538, compound

Participants

Reaction Steps

3-Amino-2-methylthieno[2,3-d]pyrimidin-4(3H)-one and 1-adamantaneacetyl chloride were reacted as described in Example 5 to provide the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 1.58-1.74 (m, 12H), 1.93-1.98 (m, 3H), 2.08-2.18 (m, 2H), 2.39 (s, 3H), 7.39 (d, J=6.0 Hz, 1H), 7.59 (d, J=6.0 Hz, 1H), 10.89 (s, 1H) ppm; MS (DCI/NH3) m/z 358 (M+H)+; Elemental Analysis: Calculated for C19H23N3O2S.0.8H2O: C, 61.37; H, 6.67; N, 11.30. Found: C, 61.50; H, 6.86; N, 11.38.

Provenance & Evidence