反应详情

(3-Chloroadamantan-1-yl)acetic acid (607.5 mg, 2.66 mmol) was dissolved in thionyl chloride (5 mL, 68.5 mmol). The reaction mixture was heated at reflux for 5 hours. The reaction mixture was cooled and then concentrated in vacuo to provide the title compound as a white solid (646.4 mg, 98%) that was used without additional purification.

1. temperatureThe reaction mixture was heated
2. temperatureat reflux for 5 hours
3. temperatureThe reaction mixture was cooled
4. concentrationconcentrated in vacuo