HCID 58956316, compound → HCID 58956314, compound

Participants

Reaction Steps

N-Cyclopropylsulfonyl-3-nitrobenzylamine was dissolved in methanol (50 mL) and to the solution was added 10% Pd—C. The reaction mixture was reacted under hydrogen atmosphere (˜40 psi) for 2 h. The catalyst was filtered off over celite and washed with methanol. The filtrate was evaporated to give N-cyclopropylsulfonyl-3-aminobenzylamine. 1H NMR (DMSO-d6): δ 0.88 (d, J=6.6 Hz, 4H), 2.44 (m, 1H), 4.00 (d, J=6.3 Hz, 2H), 5.08 (br, 2H), 6.44 (t, J=9.0 Hz, 2H), 6.53 (s, 1H), 6.94 (t, J=7.8 Hz, 1H), 7.46 (t, J=6.6 Hz, 1H).

Provenance & Evidence