HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 9-Bromo-6-fluoro-8-methoxythieno[2,3-c]quinolin-4(5H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 6-Fluoro-8-methoxythieno[2,3-c]quinolin-4(5H)-one | HCID 67447274 | — |
| Product | 9-Bromo-6-fluoro-8-methoxythieno[2,3-c]quinolin-4(5H)-one | HCID 67448756 | 61% |
Reaction Steps
Following Step 4 from General Procedure A, 6-fluoro-8-methoxythieno[2,3-c]quinolin-4(5H)-one (1.0 g, 4.0 mmol) was reacted with N-bromosuccinimide (570 mg, 4.8 mmol) to afford the desired product (800 mg, 61%) as a brown solid: ESI MS m/z 329 [C12H7BrFNO2S+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962648B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-072306e68eb844e7964088d4b783f0e0 |
| Source note | uspto-grants-2015_02 |