HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one | HCID 67450840 | — |
| Product | 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one | HCID 67450006 | 83% |
Reaction Steps
Following Step 4 from General Procedure A, 8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one (6.4 g, 26 mmol) was reacted with N-bromosuccinimide (5.0 g, 26 mmol) to afford the desired product (7.0 g, 82%) as a brown solid: ESI MS m/z 329 [C12H7BrFNO2S+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962648B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-d55d6652500e4a33b9ac82b843914eca |
| Source note | uspto-grants-2015_02 |