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HRID1853667

反应详情

EQUATION

反应方程式

HRID 1853667 的结构方程式

REACTANTS

反应物

2
结构：COc1cc(C)c2[nH]c(=O)c3sccc3c2c1Br
HCID67450006

未命名化合物

结构：C[C@H](CNC(=O)OC(C)(C)C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1
HCID67452222

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc([C@H](C)CNC(=O)OC(C)(C)C)cc1
HCID67450215

未命名化合物

收率 62%

PROCEDURE

实验过程

Following General Procedure B, 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one (150 mg, 0.46 mmol) was reacted with (S)-tert-butyl2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propylcarbamate (251 mg, 0.69 mmol) to afford the desired product (135 mg, 62%) as a light brown solid: ESI MS m/z 479 [C27H30N2O4S+H]+.