HuagongsheHuagongshe Chemistry Print Report · For research reference only
9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one → HCID 67448685, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one | HCID 67450006 | — |
| Reactant | (R)-tert-butyl 2-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propylcarbamate | HCID 86689453 | — |
| Product | HCID 67448685 | HCID 67448685 | 34% |
Reaction Steps
Following General Procedure B, 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one) (1.0 g, 3.3 mmol) was reacted with (R)-tert-butyl 2-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propylcarbamate (1.1 g, 3.0 mmol) to afford the desired product (510 mg, 34%) as a yellow solid: ESI MS m/z 497 [C27H19FN2O4S+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962648B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-2542f5e4199442b98700a11925ee9b8c |
| Source note | uspto-grants-2015_02 |